Do Antibiotic Beads Need to be Removed?

Authors

  • Jonah Davies Department of Orthopedic Surgery, Harborview Medical Center, University of Washington, Seattle, WA, USA
  • Moamen Elhaddad Department of Orthopedic Surgery, Harborview Medical Center, University of Washington, Seattle, WA, USA
  • Navin Fernando Hip and Knee Center at Northwest Primary and Specialty Care North Seattle, University of Washington, Seattle, WA, USA
  • Reza Firoozabadi Department of Orthopedic Surgery, Harborview Medical Center, University of Washington, Seattle, WA, USA
Abstract:

Background: Polymethylmethacrylate antibiotic impregnated beads can be an effective treatment for chronicosteomyelitis or an adjuvant in the treatment of open fractures. It remains unclear however whether the beads causelong-term adverse events if not removed. The purpose of this study was to determine if removal of antibiotic beads wasrequired in order to avoid long term complications.Methods: A retrospective chart review was conducted on patients with an extremity or pelvis fracture that hadimplantation of polymethylmethacrylate (PMMA) antibiotic beads over a five-year period.Results: Fifty-one patients met inclusion criteria for this study; thirty-seven patients (73%) did not have complicationsafter surgical debridement and placement of PMMA antibiotic beads necessitating removal.Conclusion: Our findings suggest that polymethylmethacrylate antibiotic beads can be utilized as a means of deliveringhigh-dose concentrations of local antibiotics and do not have to be removed in all patients.Level of evidence: III

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Journal title

volume 8  issue 4

pages  502- 505

publication date 2020-07-01

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